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(Medical-NewsWire.com, December 24, 2019 ) Market Overview
• Organ-on-chip is a multi-channel 3-D micro fluid cell culture ship which stimulates activities, mechanisms, physiological responses of entire organs.
• These micro devices are translucent, they provide a window to watch inner workings of human organs. This technology is being used to develop a whole pipeline of human organs-on-chip such as lung, gut, liver, heart, skin, bone marrow, pancreas, kidney and even a system that mimics the blood brain barrier.
• These organ-on-chip help pharmaceutical companies in replacing animal cells, comparison studies between humans and animals, the study of the toxicity of drugs and cosmetics, developing vaccines and drugs to counter bioterrorism threats, etc.,
• The global organ-on-chip market was worth YY billion in 2018 and is forecasted to reach YY billion by 2026, at a CAGR of YY% during the forecast period.
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Market Drivers
1. The provision of research funds grants is considered as the key driver for the progress in the development of OOC devices and also positively impacts its market growth globally
2. In 2017, NCATS awarded a research grant of 2 million to Emulate, Inc., to use its human Brain-Chip model and develop a fully automated research platform, to conduct experiments on the International Space Station.
3. In 2017, In 2017, NCATS and its NIH collaborators funded an estimated 15 million in the fiscal year 2017 to fund 13 awards for the ‘Tissue Chips for Disease Modeling and Efficacy Testing initiative.’
4. The surge in demand for organ-on-chip devices in the healthcare industry is expected to boost the growth of the global organ-on-chip market. Real-time imaging, in-vitro analysis of biochemical, and genetic & metabolic activities of living cells in functional tissues are some of the applications of organ-on-chip devices in the industry.
Restraints
• Major factors hindering the global organ-on-chip market are the high cost of devices because of the high manufacturing cost associated with complex manufacturing techniques.
Market Segmentation
• Global organ-on-chip market is segmented by model and end users. Model type includes Liver-On-chip model, Lung-on-chip model, Heart-on-chip model, Kidney-on-chip model, Tumor models, Custom & Multi-organ-on-Chip models, and others, end users includes pharmaceutical companies, research organizations, and others
• Rise in mortality rate due to an increase in the incidence of liver diseases such as hepatitis B, is expected to propel the demand for the liver-on-chip microfluidic model. Additionally, the surge in demand for liver-on-chip devices for drug screening is expected to fuel market growth.
Geographical Analysis
• The global organ-on-chip market is segmented into North America, Europe, Asia Pacific, South America, and Middle East & Africa.
• North America dominate the global organ-on-chip due to a surge in adoption of organs-on-chips over 2D and 3D cell cultures.
• Furthermore, rise in demand for organ-on-chip (OOCs) in drug screening, especially in the U.S., the rise in R&D initiatives and increase in a number of key players of OOCs in North America are expected to fuel the growth of the market in the coming years.
• On April 11, 2017, FDA announced a multi-year research and development agreement with a company called Emulate Inc. to test the company’s “Organs-on-Chips” technology in laboratories at the agency’s Center for Food Safety and Applied Nutrition.
Competitive Trends
• Collaborative partnerships among the key players for research and development of advanced technology in the field of organ-on-chip and new product launches are driving the global organ-on-chip market.
• In May 2018, Emulate, Inc. has formed a collaborative partnership with AstraZeneca’s Innovative Medicines and Early Development (IMED) Biotech Unit to embed its Organs-on-Chips technology within the laboratories of the IMED Drug Safety organization.
• In May 2018, CN Bio Innovations globally launched an organ-on-a-chip device that allows scientists to test potential drugs on living human organ models.
• In October 2017, InSphero AG and Charles River Laboratories International, Inc. announced a partnership for the development of 3D InSight™ PDX Microtissues and expansion of in vitro oncology services.
• In September 2017, AxoSim Technologies received a USD 1.7 million grant to expand its research aimed at fixing issues in pharmaceutical development.
• Major market players in the Organ-on-chip market are CN Innovations Holdings Limited, Emulate, Inc., Axosim Technologies LLC, CN Bio Innovations, Kirkstall Limited, Insphero Ag, Mimetas B.V., Nortis Inc., Tissuse Gmbh, Organovo Holdings, Inc., and Hesperos Inc.
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