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(Medical-NewsWire.com, April 06, 2013 ) San Francisco, CA -- The latest study of obesity is showing that genes that are active within a person's belly fat may actually be different than those found within thigh fat. The findings within the study may create a paradigm shift on the way we approach the unwanted-fat problem that afflicts so many across the globe.
The study took a variety of samples of fat from male and female participants and compared the genes of each in order to find which were more active. The main results of the study, which were conducted by Steven Smith and Sanford-Burnham Metabolism and Diabetes Translational Research Institute, showed that the belly fat is linked to a higher risk of diseases like diabetes and heart disease. Conversely, the fat around the hips and high fat does not play a role in these conditions at all.
Smith found that belly and thigh fat differ in their genetic make-up altogether. The results have showed in men, where 125 genes are expressed differently in the belly when compared to the fat in the thighs. In women, the difference is 218 genes in total.
The study noted that most directly, genes which differed are those that referred homeobox genes. These genes are known for their role in assisting in the shaping and development of the embryo. The job of the gene is to determine the placement of organs and cells. They are thus influenced by oestrogen and other hormones.
Smith noted that the homeobox genes are important as they can actually program fat cells to respond in different ways to the external signals and hormones. That means that the difference between fat in the thigh and that of the bell is pre-programmed and are genetically destined to end up in particular areas. In other words, there is a a predetermined selection of where fat will end up. It is something many have stated and speculated, without knowing exactly how it was accomplished. With the new research, it has become more clear.
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Source: EmailWire.Com 
Source: EmailWire.com
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