73 drugs lost exclusivity in 2025

In 2025, the FDA approved 73 first-time generic drugs. 

Here are the generics and their indication, in order of approval date: 

Note: The FDA’s information is current as of Dec. 18. 

1. Phytonadione injection — For select coagulation disorders.

2. Esomeprazole magnesium for suspension — For short-term treatment of erosive esophagitis.

3. Regorafenib tablet — For metastatic colorectal cancer. 

4. Mesna…