Exploring marine-derived bacterial compounds targeting the μ-opioid receptor agonists through metabolic profiling to molecular modeling

Physicochemical analysis of marine sediment

The physicochemical analysis, presented in Supplementary Table S1, includes pH, salinity, and organic matter, was conducted for four marine sediment samples collected from different regions of Bejaia, Algeria. These parameters are key environmental factors influencing microbial diversity³¹. Results indicated that all sites exhibited alkaline conditions (pH 7.78–8.13), likely due to carbonate-rich…