IBD Linked to Colon Cancer Through TL1A-Driven Immune Pathway

by Newsroom


IBD and CRC
Enhanced image showing where genes are active in colon tissue, revealing neutrophils located close to pre-cancerous epithelial cells [Longman Lab]

It is known that inflammatory bowel disease (IBD) increases the risk of colorectal cancer (CRC). But the underlying mechanism—and the genetic drivers—between this link remain yet to be determined. Genetic variants in TNFSF15, encoding tumor necrosis factor (TNF)-like cytokine…



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