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(Medical-NewsWire.com, August 18, 2016 ) Protein A, a staphylococcus aureus cell wall protein, binds to mammalian immunoglobulin through its fragment crystallizable (Fc) region. It is mainly involved in antibody purification as well as immunoprecipitation techniques in the life sciences industry. Biopharmaceutical companies, contract manufacturing organizations (CMOs) and academic institutes are using protein A resins for research purpose to separate antibodies from ascites fluid, serum (polyclonal antibody), or from the culture supernatant of a hybridoma cell line (monoclonal antibody). Protein A resin is one of the major type among other chromatography resin and it is available in two variants such as native protein A or recombinant protein A and chemically modified protein A. Recombinant protein A is also called Mabselect protein A and is one of the widely used in a biopharmaceutical research to purify the antibodies. Over the last few years, companies are manufacturing protein A with different matrixes such as agarose matrix, glass or silica based matrix and organic polymer based matrix to increase the stability and to speed up the purification process. Protein A resin is reusable and its binding capacity decreases with every purification step. Chemically modified protein A resin is more stable and its binding capacity decreases slowly when compared with natural protein A resin and is mainly used in the clinical research laboratories and academic institutes for immuneprecipitation processes.
Protein A Resin Market: Drivers and Restraints
Over the past few years, research on monoclonal antibodies is increased notably, and is expected to drive the overall Protein A Resin Market. Moreover, the increasing production of monoclonal antibodies in contract manufacturing organizations is also expected to drive the sales of protein A resin. However, the cost of the protein A is high when compared with other chromatography resins and is one of the major restraint for the overall protein A market. Increasing awareness about alternate methods for purification of monoclonal antibodies is another factor which is expected to hamper the sales of protein A resin over the forecast period. Raising government funds on monoclonal antibodies and increasing R&D expenditure between the companies to research on antibodies is also expected to drive the sales of protein A resin. The key players in the protein A resin market are manufacturing next generation protein A to overcome the traditional protein A resin issues such as leaching of ligand and alkaline stability.
Protein A Resin Market: Segmentation
Protein A resin market is segmented into following types
By Product Type
Native Protein A Resin
Recombinant Protein A Resin
By Matrix Type
Glass or Silica Based
Agarose-based
Organic Polymer Based
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By Application
Immunoprecipitation (IP)
Antibody Purification
By End User
Biopharmaceutical Manufacturers
Clinical Research Laboratories
Academic Institutes
Protein A Resin Market: Overview
Globally, Increase in research on monoclonal and polyclonal antibodies is expected to drive the overall protein A resin market and is expected to register a healthy CAGR over the forecast period.
Protein A Resin Market: Region- wise Outlook
Depending on geographic regions, the global protein A resin market is segmented into seven key regions: North America, Latin America, Eastern Europe, Western Europe, Asia Pacific excluding Japan, Japan and Middle East & Africa.
Currently, overall protein A resin market share is high in North America and is expected to remain same during the forecast period followed by western Europe and Eastern Europe. Asia pacific region is expected to register highest growth rate during the forecast period. In Asia pacific region, favorable government policies for startup companies in across all domains including healthcare is one of the major factor and is expected to drive the sales of protein A resin over the forecast period.
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Protein A Resin Market: Key Players
Some of the key players in this market are
Thermo Fisher Scientific
Repligen
Tosoh Bioscience
EMD Millipore
Novasep
GenScript
Expedeon Ltd
Kaneka Corporation
JSR Life Sciences Corporation
Future Market Insights
Abhishek Budholiya
2076928790
abhishek.b@futuremarketinsights.com
Source: EmailWire.Com 
Source: EmailWire.com
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