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(Medical-NewsWire.com, November 25, 2016 ) Ulcerative colitis is a chronic inflammatory bowel disease (IBD) that causes ulcers in the innermost lining of the colon and rectum. The colons ability to absorb water is decreased, which leads to progressive loosening of the stool, bloody stool, and sometimes cramping or abdominal pain with urgency for bowel movement (CDC, 2013; NDDIC, 2013). The exact cause or triggers of the disease are yet to be identified. Globally, the incidence of ulcerative colitis varied from 0.34 cases per 100,000 population in China to as high as 15.1 cases per 100,000 population in the UK in the 1990s (Lok et al., 2008; Shivananda et al., 1996). The diagnosed prevalence of the condition ranged between 6.3 cases per 100,000 population in China in 2006 and 243 cases per 100,000 population in the UK during 20002002 (Lok et al., 2008; Rubin et al., 2000).
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GlobalData epidemiologists forecast that there were 134,109 incident cases of ulcerative colitis in the 10MM in 2012, and the number of incident cases will grow 12.2% over the next decade to 150,530 incident cases. In 2012, there were 1,860,616 prevalent cases of ulcerative colitis in the 10MM. Each of the 10MM, except Germany, will see an increase in prevalent cases over the 10-year forecast period.
This forecast is supported by historical data for ulcerative colitis gathered from peer-reviewed journals and country-specific studies, in addition to reports taken from national health authorities and international organizations with interests in gastroenterology or inflammatory bowel disease (IBD). Another major strength of this analysis is that to take into account historical trends of ulcerative colitis and provide a robust forecast, GlobalData epidemiologists conducted linear regression analysis whenever sufficient historical data were available and the literature supported the resulting trend.
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Table of Contents
1 Table of Contents
1 Table of Contents 4
1.1 List of Tables 6
1.2 List of Figures 7
2 Introduction 8
2.1 Catalyst 8
2.2 Related Reports 9
2.3 Upcoming Reports 9
3 Epidemiology 10
3.1 Disease Background 10
3.2 Risk Factors and Comorbidities 11
3.2.1 Being Caucasian and Jewish can increase the risk of ulcerative colitis by almost 37 times 12
3.2.2 Family history of ulcerative colitis in first-degree relatives can increase the risk of ulcerative colitis almost three-fold 13
3.2.3 Current smokers have a lower chance of getting ulcerative colitis than former smokers or never smokers 13
3.3 Global Trends 15
3.3.1 US 16
3.3.2 5EU 19
3.3.3 Japan 22
3.3.4 Canada 24
3.3.5 China 26
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